Does your voice sound husky in the mornings? Is your speech becoming heavier, losing its natural tone? If you’re a woman who smokes, these changes might indicate something more serious than you think: Reinke’s edema.

What Is Reinke’s Edema?

Reinke’s edema is a soft tissue swelling caused by fluid accumulation in a special space within the vocal cords called Reinke’s space. It typically affects both vocal cords and results in a deep, hoarse voice and a feeling of vocal fatigue.

Biggest Risk: Women and Smoking

This condition is more common in women. That’s because female vocal cords are structurally thinner and have greater vibratory sensitivity, making them more susceptible to edema.
But the main culprit is clear: long-term cigarette smoking.

Smoking dries out, irritates, and damages the vascular structure of the vocal cords. The harmful chemicals in cigarettes turn the tissues in Reinke’s space spongy over time, paving the way for fluid buildup and edema.

If you’re a woman who smokes, your risk of developing Reinke’s edema is significantly higher.

What Are the Symptoms?

– Deep, low-pitched, and hoarse voice (especially noticeable in the mornings) – Vocal fatigue during speech – Loss of vocal tone and richness – Frequent need to clear the throat – Shortness of breath (in advanced cases)

How Is It Diagnosed?

Diagnosis is made through a camera-based examination called laryngoscopy, which allows direct observation of the vocal cords. If needed, videostroboscopy is used to analyze vocal cord vibrations. These tests help determine the severity and extent of the edema.

How Is It Treated?

Surgical intervention is the definitive treatment for advanced Reinke’s edema.

Laser-Assisted Microsurgery

Surgery is performed through the mouth using a procedure called microlaryngoscopy. During the procedure, a CO₂ laser is used to carefully remove the swollen tissue, drain the fluid, and preserve the natural vibration of the vocal cords.
This surgery truly involves a laser. Unlike many so-called “laser surgeries,” the laser is an essential and active tool in Reinke’s edema treatment.

Postoperative Period

– Voice rest is essential during the first week – Smoking must be stopped, and exposure to secondhand smoke avoided – Voice therapy may be recommended – Full recovery is typically achieved within a few weeks

Can It Turn Into Cancer?

Reinke’s edema is a benign condition and does not directly lead to cancer. However, long-term smoking can cause other cellular changes in the vocal cords, so regular monitoring is important.

How to Prevent It?

– Quit smoking – Practice vocal hygiene (avoid shouting, prolonged speaking) – Treat acid reflux if present – Professional voice users should seek voice therapy support

Final Note

Your voice is part of your identity—value it before you lose it. If you’re a woman and notice changes in your voice, don’t take them lightly. Especially if you smoke, your voice may be quietly calling out for help.

Prof. Dr. Gediz Murat Serin

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    Prof. Dr. Gediz Murat Serin